Macrodosing Research Chemicals (High doses)

4-HO-MET (4-hydroxy-N-methyl-N-ethyltryptamine) is a synthetic research chemical from the class of tryptamine analogues, available in higher concentrations for analytical and scientific research.

In online search behaviour, 4-HO-MET is frequently searched as mushroom drops. This reflects search language only and does not constitute a chemical or substantive equivalence: 4-HO-MET is a fully synthetic substance and is not derived from mushrooms or truffles. The substance does not fall under Dutch drug legislation and is offered exclusively for analytical and scientific research. For detailed background information on the chemical properties of 4-HO-MET, please visit the knowledge page on Microdose.nl.

• High dose 4-HO-MET drops – liquid solution in higher concentration
• Macrodose 4-HO-MET pellet blister (10x21mg) – solid research reference
• High Dose 4-HO-MET pellets (4x20mg) – solid research reference

1cP-LSD (1-cyclopropionyl-d-lysergic acid diethylamide) is a semi-synthetic research chemical from the class of lysergamide analogues, available in this category in higher concentrations than in the microdose variant. The substance does not fall under Dutch drug legislation and is offered exclusively for analytical and scientific research.

• High Dose 1cP-LSD Drops (1000mcg) – liquid solution in high concentration
• 4x100mcg 1cP-LSD blotters – absorbent carriers for analytical research

Microdosing.shop offers research chemicals in two concentration categories. The distinction lies exclusively in the amount of active substance per unit, not in the substance itself.

• RC Microdose (low): lower concentration per unit, suitable for research setups studying small quantities. View the RC Microdose category.
• RC High Dose: higher concentration per unit, suitable for research setups requiring larger amounts of active substance per unit.

Not sure which category you need? Contact us via our contact page.

The substances in this category, including 1cP-LSD and 4-HO-MET, are currently not listed under the Dutch Opium Act. Microdosing.shop only offers substances that, to the best of our knowledge at the time of listing, are not explicitly included on national prohibited substances lists.

Research chemicals are not shipped to countries where import or possession is not permitted, including Germany, Austria, the United Kingdom, Switzerland, Norway, Northern Ireland, Malta, the Canary Islands and Hungary. Shipping outside the European Union is not possible. It is the buyer's responsibility to verify local laws and regulations before placing an order.

For those looking to explore the broader scientific and educational context around microdosing, the Microdosing Institute offers comprehensive educational programmes and professional guidance. The Microdosing Institute was founded in 2017 and has trained more than 70 certified facilitators worldwide. Microdose.nl is an official partner of the Microdosing Institute.

What are mushroom drops and how do they relate to 4-HO-MET?

Mushroom drops is a widely used search term for liquid research chemicals that are structurally related to psilocin. 4-HO-MET (Methylcybin) is a synthetic research chemical structurally related to psilocin, but is not an extract from mushrooms or truffles. The substance is offered exclusively as a research substance via Microdosing.shop, not as a consumer product.

What is the difference between the high dose and microdose variant of 4-HO-MET?

Both variants contain the same substance, 4-HO-MET, but in a different concentration per unit. The microdose variant contains a lower amount of active substance per unit and can be found in the RC Microdose category. The high dose variant contains a higher concentration per unit, suitable for research setups requiring larger amounts per unit.

What is the difference between the high dose and microdose variant of 1cP-LSD?

The microdose variants of 1cP-LSD contain lower concentrations per unit. The High Dose 1cP-LSD Drops in this category contain 1000mcg per bottle, suitable for research setups requiring a higher concentration per unit. Both variants are offered exclusively for analytical and scientific research.

Are high dose research chemicals legal in the Netherlands?

The substances in this category, including 1cP-LSD and 4-HO-MET, are currently not listed under the Dutch Opium Act. Legal status can vary by country and changes regularly. Verifying applicable legislation in the country of destination is always the buyer's responsibility.

Where can I find more information about 1cP-LSD and 4-HO-MET?

Detailed background information on the chemical properties, legality and scientific context of 1cP-LSD and 4-HO-MET is available on the knowledge page of Microdose.nl, Europe's first microdosing webshop.

The research chemicals on this page are not food products, food supplements or medicines. They are offered exclusively for analytical, educational and scientific research. These substances have not been approved for human or animal consumption and do not fall under food safety legislation as consumer products. The information on this page does not constitute encouragement to use, consume or apply these substances outside a research environment.

The legal status of research chemicals differs per country and may change. It is the buyer's responsibility to verify applicable laws and regulations in the country of destination before placing an order. Not suitable for persons under 18 years of age. Keep out of reach of children.